Awais Javed

The paper identifies JUNB as a gene driving species-specific cortical features by comparing gene expression in mouse, human, and human cortical organoids.

The paper generates a single-cell multiomic atlas of the embryonic mouse thalamus, identifies two major glutamatergic lineages, and reveals early lineage divergence that segregates sensory and non-sensory circuits.

The paper identifies two distinct astrocyte lineages in the mouse neocortex using single-cell RNA sequencing and TrackerSeq, revealing their developmental origins and regulatory mechanisms.

The paper identifies regional differences in progenitor dynamics during brain development, showing sustained neurogenesis in the forebrain and transient neurogenesis in the hindbrain, driven by differences in cell cycle length and progenitor consumption.

This study identifies Pou3f1 as a master regulator of contralateral retinogeniculate projections by controlling a gene regulatory network in developing mouse retinal ganglion cells.

This study shows that temporal identity factors can reprogram adult Muller glial cells and fibroblasts into neurons in mice, using scRNA-seq to validate the transcriptional changes.

This study shows Ikzf1 and Ikzf4 regulate distinct cell fates in the mouse retina through different cis-regulatory elements and temporal expression patterns.

This study shows that Atoh7 is essential for RGC survival but not for their specification, as RGCs can develop without Atoh7 when apoptosis is inhibited.