Author

Tian-Le Xu

Shanghai Jiao Tong University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Neuroscience· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2

Frequent Co-Authors

Bo Li· 1 shared Bo PengiD· 1 shared Dehua WuiD· 1 shared Fan JiangiD· 1 shared Fan ZhangiD· 1 shared Hengyue ShiiD· 1 shared Hong JiangiD· 1 shared Jia-Ze Ruan· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperNeuroscience

Bo Li

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2 papers

Recent·Most cited

Microglial pruning of extinction-ensemble synapses preserves fear memory

Yongling Wang, Yue Cao, Taohui Liu, Tian-Tian Shi, Yaoguang Zhao, Zhihao Jin, Xiaoyu Yang, S Y Wang, Jia-Ze Ruan, Fan Zhang, Wei-Ke Li, Yang He, Sheng-Jie Lin, Wenying Xu, Xin Yi, , Tian‐Le Xu

The paper shows microglia preserve fear memory by selectively pruning extinction-ensemble synapses through local signaling cues during memory retrieval.

bioRxiv · May 7, 2026 · PreprintNeuroscience

Post-weaning social isolation impairs the orbitofrontal cortical circuit subserving contagious pain and prosocial behaviors

Yu Gong, Su-Shan Guo, Xue Chen, Zichen Zhang, Xing-Lei Song, Qin Jiang, Ying Li, Dehua Wu, Tingting Zhang, Xuan Zhao, Fan Jiang, Hong Jiang, Ming‐Gang Liu, Tian-Le Xu

This study shows that post-weaning social isolation impairs empathic behaviors in mice by disrupting glutamatergic signaling in the orbitofrontal cortex.

bioRxiv · Dec 17, 2025 · PreprintNeuroscience