Author

Tien-Hao Chen

New England Biolabs (United States)

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1

Frequent Co-Authors

Nan DaiiD· 2 shared Bijoyita RoyiD· 1 shared Erbay YigitiD· 1 shared Ira SchildkrautiD· 1 shared Jennifer L. OngiD· 1 shared Matthew J. SzucsiD· 1 shared Vladimir PotapoviD· 1 shared Zhiyi SuniD· 1 shared

Activity by Year

2022-2026 · peak 1/yr

Co-Author Collaboration Network

8 top collaborators · 16 mutual co-author links

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2 shared papersBiochemistry

Nan DaiORCID

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Author profile →

2 papers

Recent·Most cited

Adenosine Deamination by HPAMPD Reveals Structural Constraints on Adenosine Accessibility in RNA

Matthew J. Szucs, Tien-Hao Chen, Zhiyi Sun, Erbay Yigit, Nan Dai, Ira Schildkraut

This study shows that HPAMPD deaminates RNA adenosines preferentially at terminal ends and in loop regions, influenced by structural features like base pairing and magnesium-dependent folding.

bioRxiv · Oct 19, 2026 · PreprintBiochemistry

Improving the fidelity of uridine analog incorporation during in vitro transcription.

Tien-Hao Chen, Vladimir Potapov, Nan Dai, Jennifer L. Ong, Bijoyita Roy

This study evaluates the fidelity of uridine analog incorporation during in vitro transcription using different RNA polymerases and introduces a protocol to improve incorporation fidelity without affecting RNA yield.

bioRxiv · Apr 12, 2022 · PreprintMolecular Biology