A genome-wide CRISPR screen supported by human genetics identifies the TNRC18 gene locus as a novel regulator of inflammatory signaling
Fedik Rahimov, Sujana Ghosh, Sakina M. Petiwala, Mary Schmidt, Eugene Nyamugenda, Jason W. Tam, Daniel Verduzco, Sanjana Singh, Victor Avram, Apexa Modi, Celso A. Espinoza, Charles Lu, Jing Wang, Ashleigh Keller, Michael P. Macoritto, , Joshua D. Stender
A genome-wide CRISPR screen and genetic analysis identify TNRC18 as a novel regulator of IL-1β production and a risk factor for inflammatory diseases.
bioRxiv · Oct 4, 2023 · PreprintGenomics