Outer Membrane Vesicles Secreted by Bacteroides fragilis Inhibit CFTR Chloride Secretion by Human Colon Organoids
Roxanna Barnaby, Amanda B. Nymon, Paige Salerno, Carolyn Roche, Young Ah Goo, Byoung-Kyu Cho, Timothy B. Gardner, Zdeněk Švindrych, Douglas J. Taatjes, Thomas H. Hampton, Benjamin D. Ross, Bruce A. Stanton
This study shows that Bacteroides fragilis outer membrane vesicles reduce CFTR Cl- secretion in human colon organoids, with BFT-2-containing vesicles being more effective.
Infection and Immunity · May 29, 2026Peer-reviewedMicrobiology