Author

Timothy J. Mitchison

Harvard UniversityPrimary ORCID profile (0000-0001-7781-1897 · 1 paper)Unclaimed ORCID profile · follow to get notified of new preprints

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Timothy J. MitchisoniD1 paper

Biology Disciplines

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Developmental Biology· 2 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Assay:proteomics· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Assay:imaging· 1 Approach:mechanistic / dynamical model· 1

Frequent Co-Authors

Christine M. FieldiD· 2 shared Ai KiyomitsuiD· 1 shared Akankshi MunjaliD· 1 shared Anna PostnikovaiD· 1 shared Édouard HannezoiD· 1 shared Grace S. LeeiD· 1 shared Ilhan Ali· 1 shared Julissa Tello· 1 shared

Activity by Year

2021-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

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2 shared papersCell Biology

Christine M. FieldORCID

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Author profile →

3 papers

Recent·Most cited

Local fluidization of an active cytoplasmic gel partitions large cells

Luolan Bai, Christine M. Field, Ai Kiyomitsu, Yunyi Shen, Natalia D. Orlovsky, Tomomi Kiyomitsu, Timothy J. Mitchison

The paper shows that cytoplasm in early embryos behaves as a locally switchable active material, enabling long-range transport of components during cleavage.

bioRxiv · Aug 12, 2026 · PreprintCell Biology

Depletion of a neural cell adhesion molecule disrupts both epithelial and germ layer identity in sea anemone embryos

Anna Postnikova, Julissa Tello, Maristhela Alvarez, Grace S. Lee, Ilhan Ali, Christine M. Field, Timothy J. Mitchison, Katerina Ragkousi

This study identifies NCAM2 as essential for epithelial and germ layer organization in sea anemone embryos through proteomics and knockdown experiments.

bioRxiv · Aug 3, 2025 · PreprintDevelopmental Biology

Extracellular hyaluronate pressure shaped by cellular tethers drives tissue morphogenesis

Akankshi Munjal, Édouard Hannezo, Tony Yu-Chen Tsai, Timothy J. Mitchison, Sean G. Megason

The paper shows that hyaluronate pressure, driven by local secretion and anisotropic tissue stiffness, shapes zebrafish semicircular canals without actomyosin contractility.

Cell · Dec 1, 2021Peer-reviewedDevelopmental Biology