Author
Okinawa Institute of Science and Technology Graduate UniversityORCID 0009-0001-1281-6520Unclaimed ORCID profile · follow to get notified of new preprints
5 papers
Recent·Most cited
Ming Yang, Ai Kiyomitsu, Yutei Takahashi, Tomomi Kiyomitsu
This study shows that balanced RCC1 GEF activity is essential for organizing the specialized spindle midplane during early vertebrate cleavage divisions.
Takahiro Yamamoto, Ai Kiyomitsu, Yang Ming, Tomomi Kiyomitsu
This study shows that KIFC1 overexpression in medaka embryos causes monopolar spindles by preventing centrosome separation, leading to chromosome mis-segregation and embryonic lethality.
Luolan Bai, Christine M. Field, Ai Kiyomitsu…·Timothy J. Mitchison
The paper shows that cytoplasm in early embryos behaves as a locally switchable active material, enabling long-range transport of components during cleavage.
Ai Kiyomitsu, Luolan Bai, Tim J. Mitchison, Tomomi Kiyomitsu
The paper investigates how dynein organization in bulk cytoplasm coordinates aster growth and centrosome positioning during cleavage in large embryos.
Ai Kiyomitsu, Toshiya Nishimura, Shiang Jyi Hwang…·Tomomi Kiyomitsu
This study identifies a specialized Ran-GTP-driven spindle structure in medaka embryos that ensures accurate chromosome segregation during early cleavage divisions.