Genetic analyses led to the discovery of a super-active mutant of the RNA polymerase I
Tommy Darrière, Michael Pilsl, Marie-Kerguelen Sarthou, Adrien Chauvier, Titouan Genty, Sylvain Audibert, Christophe Dez, Isabelle Léger‐Silvestre, Christophe Normand, Anthony K. Henras, Marta Kwapisz, Olga Calvo, Carlos Fernández‐Tornero, Herbert Tschochner, Olivier Gadal
The paper identifies mutations in RNA polymerase I that enhance its activity, leading to increased rRNA production in yeast.
PLoS Genetics · May 28, 2019Peer-reviewedMolecular Biology