Author

Tom Graefenhan

University of Würzburg

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2 Neuroscience· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Organism:human· 2 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:host-pathogen & immune response· 1 Organism:mouse· 1

Frequent Co-Authors

Thorsten BischleriD· 3 shared Annika Walter· 2 shared Baerbel KieningeriD· 2 shared Iana Gadjalova· 2 shared Wulf Schneider‐BrachertiD· 2 shared Anca RathiD· 1 shared Annemarie Aue· 1 shared Annemarie SodmanniD· 1 shared

Activity by Year

2024-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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3 shared papersMicrobiology

Thorsten BischlerORCID

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3 papers

Recent·Most cited

Host response and cell fates of human U937 monocytes upon infection with vancomycin-resistant E. faecium

Annika Walter, Theresia Prenzel, Thorsten Bischler, Baerbel Kieninger, Iana Gadjalova, Tom Graefenhan, Wulf Schneider‐Brachert, Anca Rath, Jürgen H. Fritsch

This study examines how vancomycin-resistant E. faecium interacts with human U937 monocytes, showing early pro-inflammatory responses and isolate-specific cell death at later stages.

bioRxiv · Oct 21, 2026 · PreprintMicrobiology

Staphylococcus aureus triggers isolate-specific host transcriptional responses alongside TNF-R1 regulated cell death

Annika Walter, Thorsten Bischler, Marvin Jungblut, Leonhard F. Breitsprecher, Johanna Beck, Lucia Hofmann, Nicole Schäfer, Tanja Ziesmann, Silke Haerteis, Iana Gadjalova, Ute Distler, Gerti Beliu, Katherina Psathaki, Michael Hensel, Wulf Schneider‐Brachert, , Juergen Fritsch

This study shows that different S. aureus isolates trigger unique host transcriptional responses and cell death pathways, with TNF-R1 playing a key role in regulating infection outcomes in U937 cells.

bioRxiv · May 7, 2026 · PreprintMicrobiology

Adult dorsal root ganglion glial cells exhibit neurogenic potential upon reprogramming

Annemarie Sodmann, Niels Köhler, Nastaran M. Esfahani, Nina Schukraft, Annemarie Aue, Sara E. Jager, Maximilian Koch, Thorsten Bischler, Fabian Imdahl, Tom Graefenhan, Enrico Leipold, Heike Lydia Rittner, Robert Blum

This study shows adult mouse DRG glial cells can dedifferentiate into neural progenitor-like cells and express neuronal and glial markers, suggesting potential for sensory circuit regeneration.

bioRxiv · Apr 9, 2024 · PreprintNeuroscience