Sara E. Jager

This study identifies GM-CSF as a key mediator of vertebral bone marrow emergency myelopoiesis in neuropathic pain, linking meningeal immunity to pain pathogenesis.

This study shows adult mouse DRG glial cells can dedifferentiate into neural progenitor-like cells and express neuronal and glial markers, suggesting potential for sensory circuit regeneration.

This study uses in vivo calcium imaging to show that satellite glial cells show increased activity in painful states, with some signals linked to neuronal firing and others occurring independently.

This paper develops AAV-delivered dimeric peptide inhibitors of PICK1 to alleviate neuropathic pain in mice, showing long-term relief without adverse effects.

This study compares the transcriptional response of satellite glial cells to nerve injury using single-cell RNA-seq and identifies a common signature involving cholesterol biosynthesis regulation.

The paper characterizes immune responses in a neuropathic pain mouse model and develops a web-based tool for transcriptional data-mining of peripheral neuroimmune interactions.