Dysregulation of miRNAs Drives Premature GABAergic Maturation and Early Neurodevelopmental Defects in Schizophrenia
Fadumo Abdullahi Mohamed, Rolf Søkilde, Elif Bayram Orbe, Arkadiusz Nawrocki, Pia Jensen, Marion Kadlecová, Methi Wathikthinnakon, Susanna Cirera, Trine Møller, Charlotte Brasch‐Andersen, Michael E. Benros, Martin R. Larsen, Boye Schnack Nielsen, Kristine Freude
This study uses brain organoids to show that miRNA dysregulation in schizophrenia leads to premature GABAergic maturation and neurodevelopmental defects.
bioRxiv · May 27, 2026 · PreprintCell Biology