Author

Tyler Johnston

Mayo Clinic

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

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Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:mouse· 1 Assay:proteomics· 1

Frequent Co-Authors

Bruna de Gois MacedoiD· 1 shared Caio Loureiro SalgadoiD· 1 shared Carly R. StolliD· 1 shared Chloe Liliana LeffiD· 1 shared Emily WhiteiD· 1 shared Fabio Carvalho de Souza· 1 shared Henrique Borges da SilvaiD· 1 shared Igor Santiago-CarvalhoiD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperImmunology

Bruna de Gois MacedoORCID

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1 paper

Recent·Most cited

Sensing of extracellular ATP via P2RX7 drives lung tumor growth through regulatory T cell suppressive function

Igor Santiago-Carvalho, Ronaldo da Silva Francisco, Bruna de Gois Macedo, Caio Loureiro Salgado, Carly R. Stoll, Marcos Pinheiro Cione, Emily White, Tyler Johnston, Chloe Liliana Leff, Ildefonso Silva, Fabio Carvalho de Souza, Maria Regina D’Império Lima, Jessica Naomi Lancaster, Henrique Borges da Silva

This study identifies P2RX7 as a key regulator of Treg suppressive function in lung tumors, showing that targeting P2RX7 could improve lung cancer treatment by reducing Treg-mediated immune suppression.

bioRxiv · May 3, 2025 · PreprintImmunology