Author

U. Onubogu

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Organism:human· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Approach:genetic perturbation / CRISPR· 1

Frequent Co-Authors

M. Janiszewska· 2 shared A. R. Ramos· 1 shared B. F. Cravatt· 1 shared B. Karakyriakou· 1 shared C. J. Ott· 1 shared C. Vincentelli· 1 shared D. Engelhardt· 1 shared D. Remillard· 1 shared

Activity by Year

2021-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersCancer Biology

M. Janiszewska

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2 papers

Recent·Most cited

Collateral lethality between HDAC1 and HDAC2 exploits cancer-specific NuRD complex vulnerabilities

Y. Zhang, D. Remillard, U. Onubogu, B. Karakyriakou, J. N. Asiaban, A. R. Ramos, K. Bowland, T. R. Bishop, C. J. Ott, M. Janiszewska, B. F. Cravatt, M. A. Erb

The paper identifies collateral synthetic lethality between HDAC1 and HDAC2 in cancer cells and shows that targeting HDAC2 can suppress tumor growth by disrupting the NuRD complex.

bioRxiv · May 30, 2022Cancer Biology

Single-cell genetic heterogeneity linked to immune infiltration in glioblastoma.

K. A. Walentynowicz, D. Engelhardt, S. Yadav, U. Onubogu, R. Salatino, C. Vincentelli, T. O. McDonald, F. Michor, M. Janiszewska

The paper links genetic heterogeneity in glioblastoma to immune infiltration by analyzing single-cell genomic and spatial data.

bioRxiv · Sep 20, 2021Cancer Biology