Redundant mechanisms driven independently by RUNX1 and GATA2 for hematopoietic development
Erica Bresciani, Blake Carrington, Kai Yu, Erika M. Kim, Tao Zhen, Victoria Sanchez Guzman, Elizabeth Broadbridge, Kevin S. Bishop, Martha Kirby, Ursula L. Harper, Stephen Wincovitch, Stefania Dell’Orso, Vittorio Sartorelli, Raman B. Sood, Paul Liu
The paper identifies RUNX1-independent mechanisms for hematopoietic stem cell generation and shows that GATA2 and RUNX1 functionally complement each other in hematopoiesis.
Blood Advances · Sep 7, 2021Peer-reviewedGenetics