Kai Yu

This study identifies a population of neurons in the axolotl brain that, when activated by tail amputation, promote spinal cord regeneration by stimulating hormone production.

The paper analyzes genomic data from patients with FPDMM to identify germline RUNX1 variants and somatic mutations linked to clonal hematopoiesis and myeloid malignancies.

This study examines clonal hematopoiesis risk in individuals with germline ANKRD26 or ETV6 mutations, finding that ANKRD26 carriers have elevated risk while ETV6 carriers do not.

The paper constructs a molecular atlas of the human brain vasculature using single-cell RNA sequencing, revealing molecular heterogeneity and disease-related alterations in vascular cells.

The paper identifies RUNX1-independent mechanisms for hematopoietic stem cell generation and shows that GATA2 and RUNX1 functionally complement each other in hematopoiesis.

The paper introduces scTHI, a method to identify ligand-receptor interactions in glioma using single-cell RNA sequencing data from six human datasets.

This study uses single-cell RNA sequencing on multi-sector glioma biopsies to analyze tumor heterogeneity, revealing spatial patterns of invasion, progression branches, and cell-cell communication.