Author

V. A. Gutzeit

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 1 Pharmacology & Toxicology· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:cell type annotation· 2 Research Focus:drug response / drug discovery· 2 Assay:proteomics· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell-cell communication· 1 Assay:fluorescence / live-cell microscopy· 1 Approach:microscopy & imaging analysis· 1

Frequent Co-Authors

J. Broichhagen· 3 shared J. Levitz· 3 shared J. Lee· 2 shared A. Acosta Ruiz· 1 shared A. Acosta-Ruiz· 1 shared A. G. Orr· 1 shared B. Jones· 1 shared B. Mathes· 1 shared

Activity by Year

2018-2020 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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3 shared papersPhysiology

J. Broichhagen

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Author profile →

3 papers

Recent·Most cited

Interrogating surface versus intracellular transmembrane receptor populations using cell-impermeable SNAP-tag substrates

P. Poc, V. A. Gutzeit, J. Ast, J. Lee, B. Jones, E. D'Este, B. Mathes, D. Hodson, J. Levitz, J. Broichhagen

The paper introduces SBG-conjugated fluorophores to improve extracellular labeling of SNAP-fused proteins, enabling precise analysis of GPCR populations in living cells and tissues.

bioRxiv · Jan 29, 2020Physiology

Branched photoswitchable tethered ligands enable ultra-efficient optical control and detection of class C G protein-coupled receptors

A. Acosta-Ruiz, V. A. Gutzeit, M. J. Skelly, S. Meadows, J. Lee, A. G. Orr, K. Pleil, J. Broichhagen, J. Levitz

This paper develops branched photoswitchable ligands for efficient optical control and detection of class C G protein-coupled receptors, demonstrating near-complete agonism and dual imaging/manipulation capabilities.

bioRxiv · Feb 28, 2019Bioengineering

SNAP-tagged nanobodies enable reversible optical control of a G protein-coupled receptor via a remotely tethered photoswitchable ligand

H. Farrants, A. Acosta Ruiz, V. A. Gutzeit, D. Trauner, K. Johnsson, J. Levitz, J. Broichhagen

This paper introduces a method to reversibly control GPCR activity using photoswitchable ligands tethered via SNAP-tagged nanobodies.

bioRxiv · Feb 15, 2018Pharmacology & Toxicology