Podoplanin drives dedifferentiation and amoeboid invasion of melanoma
C. M. de Winde, S. L. George, A. Arp, A. C. Benjamin, E. Crosas-Molist, Y. Hari-Gupta, A. Carver, V. Imperatore, V. G. Martinez, V. Sanz-Moreno, S. E. Acton
This study shows podoplanin promotes amoeboid invasion and dedifferentiation in melanoma, suggesting it as a biomarker and therapeutic target.
bioRxiv · Jul 23, 2020Cancer Biology