Author

V. Sanz-Moreno

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 3 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:human· 4 Research Focus:cancer & tumor microenvironment· 2 Assay:proteomics· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

O. Maiques· 2 shared A. Arp· 1 shared A. C. Benjamin· 1 shared A. Carver· 1 shared A. J. Farrugia· 1 shared A. Perdrix Rosell· 1 shared B. Fanshawe· 1 shared C. M. de Winde· 1 shared

Activity by Year

2019-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 13 mutual co-author links

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2 shared papersCell Biology

O. Maiques

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

LAP1 regulates nuclear plasticity to enable constrained migration

Y. Jung-Garcia, O. Maiques, I. Rodriguez-Hernandez, B. Fanshawe, M.-C. Domart, M. J. Renshaw, R. M. Marti, X. Matias-Guiu, L. Collinson, V. Sanz-Moreno, J. G. Carlton

The paper identifies LAP1 as a regulator of nuclear plasticity that enables constrained migration in melanoma cells.

bioRxiv · Jun 23, 2021 · PreprintCell Biology

Early functional mismatch between breast cancer cells and their tumour microenvironment suppresses long term growth

A. Perdrix Rosell, O. Maiques, P. Chakravarty, L. Ombrato, V. Sanz-Moreno, I. Malanchi

The paper shows that aggressive breast cancer cells, when forced to grow in an atypical microenvironment, experience long-term growth suppression due to anti-tumoural macrophages.

bioRxiv · Jun 15, 2021 · PreprintCancer Biology

Podoplanin drives dedifferentiation and amoeboid invasion of melanoma

C. M. de Winde, S. L. George, A. Arp, A. C. Benjamin, E. Crosas-Molist, Y. Hari-Gupta, A. Carver, V. Imperatore, V. G. Martinez, V. Sanz-Moreno, S. E. Acton

This study shows podoplanin promotes amoeboid invasion and dedifferentiation in melanoma, suggesting it as a biomarker and therapeutic target.

bioRxiv · Jul 23, 2020Cancer Biology

Cdc42EP5/BORG3 modulates SEPT9 to promote actomyosin function and melanoma invasion and metastasis

A. J. Farrugia, J. Rodriguez, J. L. Orgaz, M. Lucas, V. Sanz-Moreno, F. Calvo

This study shows Cdc42EP5 regulates melanoma invasion and metastasis by modulating SEPT9 to enhance actomyosin contractility and F-actin crosslinking.

bioRxiv · Dec 2, 2019Cancer Biology