Human Gasdermin D and MLKL disrupt mitochondria, endocytic traffic and TORC1 signaling in budding yeast
M. Valenti, M. Molina, V. J. Cid
This study expresses human GSDMD and MLKL in yeast to investigate their effects on mitochondria, endocytic traffic, and TORC1 signaling, revealing their role in cell death and potential for drug discovery.
bioRxiv · Nov 29, 2022 · PreprintCell Biology