Author

V. Kankate

Thomas Jefferson University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Neuroscience· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Organism:Drosophila· 1 Organism:human· 1 Assay:proteomics· 1 Organism:rat· 1

Frequent Co-Authors

Andrew T. Nelson· 2 shared Davide TrottiiD· 2 shared K. KrishnamurthyiD· 2 shared M.E. CicardiiD· 2 shared Piera PasinelliiD· 2 shared Shashirekha S. MarkandaiahiD· 2 shared Aaron R. HaeusleriD· 1 shared Amandeep GirdhariD· 1 shared

Activity by Year

2023-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersNeuroscience

Andrew T. Nelson

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

The nuclear import receptor Kapβ2 protein modifies neurotoxicity mediated by poly(GR) in C9orf72-linked ALS/FTD

M.E. Cicardi, V. Kankate, Sindhu Sriramoji, K. Krishnamurthy, Shashirekha S. Markandaiah, Brandie Morris Verdone, Amandeep Girdhar, Andrew T. Nelson, Linda Blake Rivas, Andrew Boehringer, Aaron R. Haeusler, Piera Pasinelli, Lin E. Guo, Davide Trotti

This study shows that Kapβ2 protein interacts with poly(GR) and reduces its neurotoxicity in C9orf72-linked ALS/FTD by improving neuron survival.

Communications Biology · Mar 28, 2024Peer-reviewedNeuroscience

C9orf72 poly(PR) mediated neurodegeneration is associated with nucleolar stress

M.E. Cicardi, Justin Hallgren, Darilang Mawrie, K. Krishnamurthy, Shashirekha S. Markandaiah, Andrew T. Nelson, V. Kankate, Eric Nathaniel Anderson, Piera Pasinelli, Udai Bhan Pandey, Christine M. Eischen, Davide Trotti

This study shows that C9orf72 poly(PR) causes nucleolar stress and neurotoxicity, which can be mitigated by reducing p53 levels in fly and rat models.

iScience · Jul 28, 2023Peer-reviewedNeuroscience