Author

Christine M. Eischen

Thomas Jefferson UniversityORCID 0000-0003-4618-8996Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:differential expression· 2 Approach:experimental assay· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Assay:CRISPR screen· 1 Assay:DNA methylation· 1 Organism:Drosophila· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

Andrew T. Nelson· 1 shared Clare M. AdamsiD· 1 shared Darilang Mawrie· 1 shared Davide TrottiiD· 1 shared Eric Nathaniel AndersoniD· 1 shared Justin Hallgren· 1 shared K. KrishnamurthyiD· 1 shared M.E. CicardiiD· 1 shared

Activity by Year

2022-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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1 shared paperNeuroscience

Andrew T. Nelson

Mutual co-authors in cluster

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2 papers

Recent·Most cited

NeuroscienceiSciencePeer-reviewedJul 28, 2023

C9orf72 poly(PR) mediated neurodegeneration is associated with nucleolar stress

M.E. Cicardi, Justin Hallgren, Darilang Mawrie…·Davide Trotti

This study shows that C9orf72 poly(PR) causes nucleolar stress and neurotoxicity, which can be mitigated by reducing p53 levels in fly and rat models.

21 citations

Drosophilarat

𝕏 PostBluesky

BioinformaticseLifePeer-reviewedMay 17, 2022

Systematic lncRNA mapping to genome-wide co-essential pathways uncovers cancer dependency on uncharacterized lncRNAs

Ramkrishna Mitra, Clare M. Adams, Christine M. Eischen

The paper identifies 30 high-confidence lncRNAs critical for cancer proliferation by integrating CRISPR data with multi-omics, showing their role in cell cycle regulation and patient survival.

14 citations

humanCRISPR screen

𝕏 PostBluesky