Author

V. Kostiou

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:clustering· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

A. Herms· 2 shared B. A. Hall· 2 shared D. Fernandez-Antoran· 2 shared K. Murai· 2 shared P. H. Jones· 2 shared A. Wabik· 1 shared B. Colom· 1 shared G. Piedrafita· 1 shared

Activity by Year

2019-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

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2 shared papersCancer Biology

A. Herms

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Author profile →

2 papers

Recent·Most cited

p53 mutation in normal esophagus promotes multiple stages of carcinogenesis but is constrained by clonal competition

K. Murai, S. Dentro, S. H. Ong, R. Sood, D. Fernandez-Antoran, A. Herms, V. Kostiou, B. A. Hall, M. Gerstung, P. H. Jones

This study shows p53 mutations in normal esophagus drive clonal expansion but are constrained by clonal competition, and LOH is critical for malignant transformation.

bioRxiv · Feb 3, 2022Cancer Biology

The single-progenitor model as the unifying paradigm of squamous epithelial maintenance

G. Piedrafita, V. Kostiou, A. Wabik, B. Colom, D. Fernandez-Antoran, A. Herms, K. Murai, B. A. Hall, P. H. Jones

This study uses lineage tracing and proliferation assays to show that squamous epithelial tissues are maintained by a single population of proliferating cells, not multiple stem cell types.

bioRxiv · Jul 26, 2019Cell Biology