Author

V. L. Hewitt

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:cell type annotation· 2 Research Focus:development & morphogenesis· 2 Organism:Drosophila· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

A. J. Whitworth· 2 shared F. Polleux· 2 shared A. Morgan· 1 shared A. Vagnoni· 1 shared B. Osei· 1 shared C. C. G. Fabre· 1 shared D. Francis· 1 shared D. M. Virga· 1 shared

Activity by Year

2020-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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2 shared papersCell Biology

A. J. Whitworth

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Author profile →

3 papers

Recent·Most cited

Essential conserved neuronal motors kinesin-1 and kinesin-3 regulate Abeta42 toxicity in vivo

D. Francis, F. Paonessa, C. C. G. Fabre, V. L. Hewitt, M. E. Giannakou, I. Peset, A. J. Whitworth, R. Livesey, I. M. Palacios

This study shows that kinesin-1 and kinesin-3 mitigate Aβ42Arc toxicity in Drosophila neurons and rescue behavioral defects.

bioRxiv · Apr 23, 2024 · PreprintCell Biology

Activity-dependent subcellular compartmentalization of dendritic mitochondria structure in CA1 pyramidal neurons

D. M. Virga, S. Hamilton, B. Osei, A. Morgan, E. Zamponi, N. J. Park, V. L. Hewitt, D. Zhang, K. C. Gonzalez, E. Bloss, F. Polleux, T. L. Lewis

This study identifies an activity-dependent molecular mechanism regulating subcellular compartmentalization of dendritic mitochondria morphology in CA1 pyramidal neurons.

bioRxiv · Mar 25, 2023 · PreprintCell Biology

Decreasing pdzd8-mediated mitochondrial-ER contacts in neurons improves fitness by increasing mitophagy

V. L. Hewitt, L. Miller-Fleming, S. Andreazza, F. Mattedi, J. Prudent, F. Polleux, A. Vagnoni, A. J. Whitworth

This study shows reducing pdzd8-mediated mitochondrial-ER contacts in neurons improves fitness and lifespan by enhancing mitophagy in Drosophila.

bioRxiv · Nov 14, 2020Cell Biology