Author

V. Murugaiah

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2 Microbiology· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Assay:proteomics· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1

Frequent Co-Authors

N. Beirag· 3 shared U. Kishore· 3 shared R. Bulla· 2 shared T. Madan· 2 shared A. Mangogna· 1 shared C. Kumar· 1 shared D. Mitchell· 1 shared D. Pedersen· 1 shared

Activity by Year

2020-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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3 shared papersImmunology

N. Beirag

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Neutrophil-derived complement factor P induces cytotoxicity in basal-like cells via caspase 3/7 activation in pancreatic cancer

U. Kishore, P. Varghese, A. Mangogna, L. Klein, M. Tu, L. Urbach, M. Qiu, R. Nicolle, V. Murugaiah, N. Beirag, S. Roth, D. Pedersen, R. Sim, V. Ellenrieder, G. R. Andersen, , S. Singh

This study shows that neutrophil-derived complement factor P induces apoptosis in basal-like pancreatic cancer cells via caspase 3/7 activation, linking properdin expression to better prognosis.

bioRxiv · Oct 28, 2023 · PreprintImmunology

Human Surfactant Protein D Facilitates SARS-CoV-2 Pseudotype Binding and Entry in DC-SIGN Expressing Cells, and Downregulates Spike protein Induced Inflammation

N. Beirag, C. Kumar, T. Madan, M. H. Shamji, R. Bulla, D. Mitchell, V. Murugaiah, M. Mayora Neto, N. J. Temperton, S. Idicula-Thomas, P. M. Varghese, U. Kishore

This study shows that rfhSP-D enhances SARS-CoV-2 Spike protein binding to DC-SIGN and increases viral uptake in DC-SIGN-expressing cells while reducing inflammation.

bioRxiv · May 16, 2022Immunology

Human Surfactant Protein D Binds S1 and Receptor Binding Domain of Spike protein and acts as an entry inhibitor of SARS-CoV-2 Pseudotyped viral particles in vitro

M.-H. Hsieh, N. Beirag, V. Murugaiah, Y.-C. Chou, W.-S. Kuo, H.-F. Kao, T. Madan, U. Kishore, J.-Y. Wang

This study shows that rfhSP-D binds SARS-CoV-2 S1 protein and inhibits viral entry into cells, suggesting its potential as an antiviral therapy.

bioRxiv · Dec 18, 2020Microbiology