Author

M. Tu

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Cancer Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 3 Approach:experimental assay· 3 Organism:human· 3 Assay:bulk RNA-seq· 2 Assay:spatial transcriptomics· 2 Approach:statistical model· 2 Assay:ATAC-seq· 1 Research Focus:cell-cell communication· 1

Frequent Co-Authors

L. Klein· 2 shared L. Urbach· 2 shared U. Kishore· 2 shared V. Ellenrieder· 2 shared A. Mangogna· 1 shared A. P. Berg· 1 shared A. Papantonis· 1 shared A. Trumpp· 1 shared

Activity by Year

2021-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 32 mutual co-author links

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2 shared papersCancer Biology

L. Klein

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Spatial tumor immune heterogeneity facilitates subtype co-existence and therapy response via AP1 dichotomy in pancreatic cancer

L. Klein, M. Tu, N. Krebs, L. Urbach, D. G. Grimm, M. U. Latif, F. Penz, N. Chan, K. Aliar, F. Vyas, U. Kishore, E. Hessmann, A. Trumpp, E. Espinet, A. Papantonis, , S. K. Singh

The paper identifies AP1 transcription factor dichotomy and CD68+ macrophages as drivers of intratumoral subtype co-existence and therapy response in pancreatic cancer.

bioRxiv · Oct 30, 2023 · PreprintCancer Biology

Neutrophil-derived complement factor P induces cytotoxicity in basal-like cells via caspase 3/7 activation in pancreatic cancer

U. Kishore, P. Varghese, A. Mangogna, L. Klein, M. Tu, L. Urbach, M. Qiu, R. Nicolle, V. Murugaiah, N. Beirag, S. Roth, D. Pedersen, R. Sim, V. Ellenrieder, G. R. Andersen, , S. Singh

This study shows that neutrophil-derived complement factor P induces apoptosis in basal-like pancreatic cancer cells via caspase 3/7 activation, linking properdin expression to better prognosis.

bioRxiv · Oct 28, 2023 · PreprintImmunology

Molecular basis for the regulation of human glycogen synthase by phosphorylation and glucose-6-phosphate

T. J. McCorvie, P. M. Loria, M. Tu, S. Han, L. Shrestha, D. S. Froese, I. M. Ferreira, A. P. Berg, W. W. Yue

This study presents cryo-EM structures of phosphorylated human GYS1 complexed with GYG1, revealing how phosphorylation and glucose-6-phosphate regulate glycogen synthase activity.

bioRxiv · Nov 12, 2021Biochemistry