Author

M.-H. Hsieh

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Cell Biology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:gene regulatory network inference· 2 Organism:human· 2 Organism:mouse· 2 Assay:proteomics· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1

Frequent Co-Authors

H. Zhu· 2 shared Y. Wang· 2 shared A. Kumar· 1 shared B. B. Khadgi· 1 shared B. M. Evers· 1 shared C. Lewis· 1 shared C. Xing· 1 shared C. Zhang· 1 shared

Activity by Year

2020-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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2 shared papersCell Biology

H. Zhu

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Positive selection of somatically mutated clones identifies adaptive pathways in metabolic liver disease

Z. Wang, S. Zhu, Y. Jia, Y. Wang, N. Kubota, N. Fujiwara, R. Gordillo, C. Lewis, M. Zhu, T. Sharma, L. Li, Q. Zeng, Y.-H. Lin, M.-H. Hsieh, P. Gopal, , H. Zhu

The paper identifies adaptive pathways in metabolic liver disease by selecting somatically mutated clones in mice and humans, finding mutations that ameliorate lipotoxicity and promote clonal expansion.

bioRxiv · Mar 20, 2023Cell Biology

Cancer mutations rewire the RNA methylation specificity of METTL3-METTL14

C. Zhang, L. Tunes, M.-H. Hsieh, P. Wang, A. Kumar, B. B. Khadgi, Y.-Y. Yang, K. A. Doxtader, E. Herrell, O. Koczy, R. Setlem, X. Zhang, B. M. Evers, Y. Wang, C. Xing, , Y. Nam

The paper shows that a cancer mutation in METTL14 changes RNA methylation specificity, promoting oncogenesis by altering gene expression without increasing global m6A levels.

bioRxiv · Mar 16, 2023 · PreprintBiochemistry

Human Surfactant Protein D Binds S1 and Receptor Binding Domain of Spike protein and acts as an entry inhibitor of SARS-CoV-2 Pseudotyped viral particles in vitro

M.-H. Hsieh, N. Beirag, V. Murugaiah, Y.-C. Chou, W.-S. Kuo, H.-F. Kao, T. Madan, U. Kishore, J.-Y. Wang

This study shows that rfhSP-D binds SARS-CoV-2 S1 protein and inhibits viral entry into cells, suggesting its potential as an antiviral therapy.

bioRxiv · Dec 18, 2020Microbiology