Author

R. Guerois

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 4 Biochemistry· 3 Plant Biology· 2 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 8 Organism:human· 6 Research Focus:cell signaling & trafficking· 5 Organism:Arabidopsis· 3 Research Focus:chromatin & epigenetic regulation· 3 Research Focus:cell type annotation· 2 Research Focus:development & morphogenesis· 2 Approach:genetic perturbation / CRISPR· 2

Frequent Co-Authors

A. M. Gautreau· 2 shared A. Polesskaya· 2 shared C. Kretschmer· 2 shared H. Bret· 2 shared J. Gantner· 2 shared J. Stuttmann· 2 shared P. Cejka· 2 shared P. Legrand· 2 shared

Activity by Year

2019-2024 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 10 mutual co-author links

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2 shared papersCell Biology

A. M. Gautreau

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Author profile →

10 papers

Recent·Most cited

Disordered regions and folded modules in CAF-1 promote histone deposition in S. pombe

F. Ouasti, M. Audin, K. Freon, J.-P. Quivy, M. Tachekort, E. Cesard, A. Thureau, V. Ropars, P. F. Varela, G. Moal, I. Soumana-Amadou, A. Uryga, P. Legrand, J. Andreani, R. Guerois, , F. Ochsenbein

This study identifies how disordered regions and folded modules in SpCAF-1 from S. pombe enable histone deposition by mediating interactions with histones and PCNA during DNA replication.

eLife · Feb 20, 2024Peer-reviewedBiochemistry

Molecular insights into the activation of Mre11-Rad50 endonuclease activity by Sae2/CtIP

Y. Nicolas, H. Bret, E. Cannavo, P. Cejka, V. Borde, R. Guerois

This study reveals how Sae2/CtIP activates Mre11 nuclease activity through structural and biochemical analyses in yeast and human systems.

bioRxiv · Aug 5, 2023Biochemistry

Mechanism of DNA unwinding by hexameric MCM8-9 in complex with HROB

A. Acharya, H. Bret, J.-W. Huang, M. Muetze, M. Goese, V. Kissling, R. Seidel, A. Ciccia, R. Guerois, P. Cejka

This study investigates how HROB regulates the DNA unwinding activity of the MCM8-9 helicase complex through structural and biochemical analyses.

bioRxiv · Jun 12, 2023 · PreprintBiochemistry

PPP2R1A Regulates Migration Persistence through the WAVE Shell Complex

Y. Wang, G. Chiappetta, R. Guerois, S. Romero, M. Krause, C. Dessalles, A. Babataheri, A. I. Barakat, J. Vinh, A. Polesskaya, A. M. Gautreau

This study identifies PPP2R1A's role in migration persistence via the WAVE Shell Complex, showing its tumor suppressor function through actin regulation.

bioRxiv · Jun 2, 2022 · PreprintCell Biology

Differential requirement for the EDS1 catalytic triad in A. thaliana and N. benthamiana

J. Zoennchen, J. Gantner, D. Lapin, K. Barthel, L. Eschen-Lippold, S. Zantop, C. Kretschmer, J. E. Parker, R. Guerois, J. Stuttmann

The paper investigates the functional differences of EDS1 catalytic triad in Arabidopsis and Nicotiana benthamiana, finding lineage-specific roles in TNL immunity and PRR signaling.

bioRxiv · Dec 15, 2021Plant Biology

ComF is a key mediator in single-stranded DNA transport and handling during natural transformation

P. P. Damke, L. Celma, S. Kondekar, A. M. Di Guilmi, S. Marsin, J. Depagne, X. Veaute, P. Legrand, H. Walbott, J. Vercruyssen, R. Guerois, S. Quevillon-Cheruel, J. P. Radicella

This study identifies ComF as essential for DNA transport and handling during natural transformation in bacteria, revealing its structural features and functional role in DNA processing.

bioRxiv · Aug 4, 2021Microbiology

Restrained activation of CYFIP2-containing WAVE complexes controls membrane protrusions and cell migration

A. Polesskaya, A. Boutillon, S. Yang, Y. Wang, S. Romero, Y. Liu, M. Lavielle, N. Molinie, N. Rocques, A. Fokin, R. Guerois, B. Chen, N. B. David, A. M. Gautreau

The paper shows CYFIP2-containing WAVE complexes restrain RAC1 activation, affecting cell migration, and mutations in CYFIP2 can enhance its activity.

bioRxiv · Jul 2, 2020 · PreprintCell Biology

Patronus is the elusive plant securin, preventing chromosome separation by antagonizing separase

L. Cromer, S. Jolivet, D. K. Singh, F. Berthier, N. De Winne, G. De Jaeger, S. Komaki, M. A. Prusicki, A. Schnittger, R. Guerois, R. Mercier

The paper identifies PANS1 and PANS2 as the plant securin homologs, showing they antagonize separase to regulate chromosome separation in Arabidopsis.

bioRxiv · Apr 11, 2019Cell Biology

An EDS1-SAG101 complex functions in TNL-mediated immunity in Solanaceae

J. Gantner, J. Ordon, C. Kretschmer, R. Guerois, J. Stuttmann

The paper compares EDS1 complex functions in TNL-mediated immunity across Solanaceae species, finding that EDS1-SAG101 complexes are required in Nicotiana benthamiana, while EDS1-PAD4 complexes are functional in Arabidopsis.

bioRxiv · Mar 15, 2019 · PreprintPlant Biology

Two polybasic domains of septin9 control septin filaments assembly and Golgi integrity

M. Omrane, A. S. Camara, C. Taveneau, N. Benzoubir, T. Tubiana, J. Yu, R. Guerois, D. Samuel, B. Goud, C. Pous, S. Bressanelli, R. C. Garratt, A. R. Thiam, A. Gassama-Diagne

This study identifies two polybasic domains in septin 9 that mediate interaction with phosphoinositides and are critical for septin filament assembly and Golgi integrity.

bioRxiv · Jan 31, 2019 · PreprintCell Biology