Author

V. Rubio

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Plant Biology· 6 Biochemistry· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 9 Organism:Arabidopsis· 7 Research Focus:cell type annotation· 4 Research Focus:cell signaling & trafficking· 3 Assay:proteomics· 3 Research Focus:chromatin & epigenetic regulation· 2 Research Focus:development & morphogenesis· 2 Assay:DNA methylation· 2

Frequent Co-Authors

S. Fonseca· 4 shared M. Garcia-Leon· 3 shared C. Bourbousse· 2 shared D. Alabadi· 2 shared E. Canibano· 2 shared E. Iniesto· 2 shared F. Barneche· 2 shared J. L. Micol· 2 shared

Activity by Year

2018-2024 · peak 4/yr

Co-Author Collaboration Network

10 top collaborators · 22 mutual co-author links

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4 shared papersPlant Biology

S. Fonseca

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Author profile →

9 papers

Recent·Most cited

Modular Fluorescent Cholesterol Naphthalimide Probes And Their Application For Cholesterol Trafficking Studies In Cells

V. Rubio, N. McInchak, G. Fernandez, D. Benavides, D. Herrera, C. Jimenez, H. Mesa, J. Meade, Q. Zhang, M. J. Stawikowski

The paper develops modular fluorescent cholesterol analogs to study subcellular cholesterol trafficking, showing that head group modifications affect internalization efficiency and subcellular distribution.

bioRxiv · Jun 24, 2024 · PreprintBiochemistry

The structure of the R2T complex reveals a different architecture of the related HSP90 co-chaperones R2T and R2TP

A. Palacios-Abella, A. Lopez-Perrote, J. Boskovic, S. Fonseca, C. Urbez, V. Rubio, O. Llorca, D. Alabadi

The paper determines the cryoEM structure of the Arabidopsis R2T complex, revealing its dodecameric organization and distinct architecture compared to the human R2TP complex.

bioRxiv · Mar 27, 2024 · PreprintBiochemistry

Overlapping roles of Arabidopsis INCURVATA11 and CUPULIFORMIS2 as Polycomb Repressive Complex 2 accessory proteins

R. Nadi, L. Juan-Vicente, S. D. Lup, Y. Fernandez, V. Rubio, J. L. Micol

This study identifies ICU11 and CP2 as PRC2 accessory proteins in Arabidopsis, showing they interact with PRC2 core components and share similar transcriptomic effects with PRC2 mutants.

bioRxiv · Mar 15, 2024 · PreprintPlant Biology

The antioxidants esculetin and quercetin modulate differently redox balance in human NB4 leukemia cells

V. Rubio, A. I. Garcia-Perez, A. Herraez, L. Puebla, J. C. Diez

This study examines how esculetin and quercetin affect redox balance and apoptosis in NB4 leukemia cells, showing differential effects on cell viability and ROS levels.

bioRxiv · Feb 28, 2024 · PreprintBiochemistry

The Arabidopsis ATP-Binding Cassette E protein ABCE2 is a conserved component of the translation machinery

C. Navarro-Quiles, E. Mateo-Bonmati, H. Candela, P. Robles, A. Martinez-Laborda, Y. Fernandez, J. Simura, K. Ljung, V. Rubio, M. R. Ponce, J. L. Micol

This study identifies ABCE2 as a conserved ribosome recycling factor in Arabidopsis, showing its role in growth and vascular development through auxin metabolism.

bioRxiv · May 30, 2022Plant Biology

COP1 promotes seed germination by destabilizing RGA-LIKE2 (RGL2) in Arabidopsis

B.-D. Lee, Y. Yim, E. Canibano, S.-H. Kim, M. Garcia-Leon, V. Rubio, S. Fonseca, N.-C. Paek

The paper identifies COP1 as an upstream negative regulator of RGL2, showing COP1 promotes seed germination by ubiquitinating and destabilizing RGL2 in Arabidopsis.

bioRxiv · Dec 1, 2021 · PreprintPlant Biology

DET1-mediated COP1 regulation avoids HY5 activity over second-site targets to tune plant photomorphogenesis

E. Canibano, C. Bourbousse, M. Garcia-Leon, L. Wolff, C. Garcia-Baudino, F. Barneche, V. Rubio, S. Fonseca

This study shows DET1 stabilizes COP1 to reduce HY5 protein levels, preventing HY5 from over-activating second-site targets and causing hyper-photomorphogenic phenotypes.

bioRxiv · Sep 30, 2020Plant Biology

COP1 destabilizes DELLA proteins in Arabidopsis

N. Blanco-Tourinan, M. Legris, E. G. Minguet, C. Costigliolo-Rojas, M. A. Nohales, E. Iniesto, M. Garcia-Leon, M. Pacin, N. Heucken, T. Blomeier, A. Locascio, M. Cerny, D. Esteve-Bruna, M. Diez-Diaz, B. Brzobohaty, , D. Alabadi

This paper shows that COP1 destabilizes DELLA proteins in Arabidopsis through ubiquitination, independent of gibberellin signaling, and this process is relevant for growth responses to shade and warm temperature.

bioRxiv · Jan 9, 2020Plant Biology

DET1-mediated degradation of a SAGA-like deubiquitination module controls H2Bub homeostasis

A. Nassrallah, M. Rougee, C. Bourbousse, S. Drevensek, S. Fonseca, E. Iniesto, O. Ait-Mohamed, A.-F. Deton-Cabanillas, G. Zabulon, I. Ahmed, D. Stroebel, V. Masson, B. Lombard, D. Eeckhout, K. Gevaert, , F. Barneche

The paper shows DET1 regulates H2Bub homeostasis in Arabidopsis by controlling the stability of a DUBm through interaction with DDA1.

bioRxiv · Apr 30, 2018Plant Biology