Author

V. T. Lee

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Microbiology· 4

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 4 Research Focus:chromatin & epigenetic regulation· 2 Organism:bacteria (other)· 1 Research Focus:cell signaling & trafficking· 1 Organism:E. coli· 1 Research Focus:host-pathogen & immune response· 1 Organism:mouse· 1 Assay:proteomics· 1

Frequent Co-Authors

A. Turdiev· 3 shared H. Turdiev· 3 shared B. W. Anderson· 2 shared J. D. Wang· 2 shared J. Yang· 2 shared A. T. Belew· 1 shared C. A. Weiss· 1 shared C. L. Hall· 1 shared

Activity by Year

2019-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

3 shared papersMicrobiology

A. Turdiev

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Characterization of the Entner-Douderoff Pathway in Pseudomonas aeruginosa Catheter-associated Urinary Tract Infections

N. El Husseini, S. A. Mekonnen, C. L. Hall, S. J. Cole, J. A. Carter, A. T. Belew, N. M. El-Sayed, V. T. Lee

This study investigates the role of the Entner-Douderoff pathway in Pseudomonas aeruginosa during catheter-associated urinary tract infections, finding it dispensable in this model.

bioRxiv · Nov 14, 2023 · PreprintMicrobiology

The nucleotide messenger (p)ppGpp is a co-repressor of the purine synthesis transcription regulator PurR in Firmicutes

B. W. Anderson, M. A. Schumacher, J. Yang, A. Turdiev, H. Turdiev, Q. He, V. T. Lee, R. G. Brennan, J. D. Wang

This study shows (p)ppGpp acts as a co-repressor of PurR in Firmicutes, downregulating purine synthesis by enhancing PurR DNA binding, with implications across environments from the gut to pathogens.

bioRxiv · Dec 2, 2020 · PreprintMicrobiology

Systemic characterization of pppGpp, ppGpp and pGpp targets in Bacillus reveal NahA converts (p)ppGpp to pGpp to regulate alarmone composition and signaling

J. Yang, B. W. Anderson, A. Turdiev, H. Turdiev, D. M. Stevenson, D. Amador-Noguez, V. T. Lee, J. D. Wang

The paper identifies pGpp as a third alarmone in Bacillus and shows NahA converts (p)ppGpp to pGpp, altering alarmone composition and stress response.

bioRxiv · Mar 23, 2020 · PreprintMicrobiology

Oligoribonuclease functions as a diribonucleotidase to bypass a key bottleneck in RNA degradation

S.-K. Kim, J. D. Lormand, C. A. Weiss, K. A. Eger, H. Turdiev, A. Turdiev, W. C. Winkler, H. Sondermann, V. T. Lee

This study identifies oligoribonuclease (Orn) as a dedicated diribonucleotidase essential for completing RNA degradation by clearing diribonucleotides, which otherwise impact cellular viability.

bioRxiv · Feb 11, 2019 · PreprintMicrobiology