Author

M. A. Schumacher

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Immunology· 1 Microbiology· 1 Physiology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 3 Research Focus:chromatin & epigenetic regulation· 2 Research Focus:host-pathogen & immune response· 2 Organism:mouse· 2 Research Focus:cell type annotation· 1 Organism:human· 1 Assay:metagenomics· 1 Assay:proteomics· 1

Frequent Co-Authors

A. Waddell· 2 shared M. R. Frey· 2 shared A. Turdiev· 1 shared B. W. Anderson· 1 shared C. Potter· 1 shared C. Y. Liu· 1 shared D. Almohazey· 1 shared D. Warburton· 1 shared

Activity by Year

2020-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersImmunology

A. Waddell

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Microbiota epigenetically direct tuft cell differentiation to control type 2 immunity

E. M. Eshleman, T. Rice, C. Potter, A. Waddell, S. Hashimoto-Hill, V. Woo, S. Field, L. Engleman, M. A. Schumacher, M. R. Frey, L. A. Denson, F. D. Finkelman, T. Alenghat

This study shows that butyrate-producing bacteria epigenetically control tuft cell differentiation via HDAC3, influencing type 2 immunity and helminth responses.

bioRxiv · Mar 2, 2023Immunology

The nucleotide messenger (p)ppGpp is a co-repressor of the purine synthesis transcription regulator PurR in Firmicutes

B. W. Anderson, M. A. Schumacher, J. Yang, A. Turdiev, H. Turdiev, Q. He, V. T. Lee, R. G. Brennan, J. D. Wang

This study shows (p)ppGpp acts as a co-repressor of PurR in Firmicutes, downregulating purine synthesis by enhancing PurR DNA binding, with implications across environments from the gut to pathogens.

bioRxiv · Dec 2, 2020 · PreprintMicrobiology

Sprouty2 limits intestinal tuft and goblet cell numbers through GSK3β-mediated restriction of epithelial IL-33.

M. A. Schumacher, J. J. Hsieh, C. Y. Liu, K. L. Appel, A. Waddell, D. Almohazey, K. Katada, J. K. Bernard, E. B. Bucar, S. Gadeock, K. M. Maselli, M. K. Washington, T. C. Grikscheit, D. Warburton, M. J. Rosen, M. R. Frey

This study shows that Sprouty2 restricts intestinal tuft and goblet cell numbers via GSK3β-mediated IL-33 expression, with implications for inflammatory bowel disease.

bioRxiv · Mar 9, 2020Physiology