NeuroscienceMolecular PsychiatryPeer-reviewed
Autism-linked Cullin3 germline haploinsufficiency impacts cytoskeletal dynamics and cortical neurogenesis through RhoA signaling
Megha Amar, Akula Bala Pramod, Nam‐Kyung Yu…·Lilia M. Iakoucheva
This study shows that Cul3 haploinsufficiency in mice causes social and cognitive deficits, cortical volume reduction, and cytoskeletal defects, which are rescued by RhoA inhibition.
50 citationstop 3%