Author

W. C. Gause

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Research Focus:cell signaling & trafficking· 2 Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Organism:mouse· 2 Research Focus:differential expression· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

A. Lemenze· 2 shared F. Chen· 2 shared W. Wu· 2 shared A. Rivera· 1 shared D. J. Smyth· 1 shared D. W. El-Naccache· 1 shared J. J. Ponessa· 1 shared J. S. Weinstein· 1 shared

Activity by Year

2020-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 35 mutual co-author links

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2 shared papersImmunology

A. Lemenze

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Author profile →

2 papers

Recent·Most cited

A helminth mimic of TGF-β, TGM, enhances regenerative cutaneous wound healing and modulates immune cell recruitment and activation

K. E. Lothstein, F. Chen, P. Mishra, D. J. Smyth, W. Wu, A. Lemenze, Y. Kumamoto, R. M. Maizels, W. C. Gause

This study shows that TGM, a helminth-derived TGF-β mimic, accelerates wound healing and reprograms macrophage activation through TGF-β receptor interactions.

bioRxiv · Sep 24, 2022 · PreprintImmunology

Lung macrophages mediate helminth resistance through differential activation of recruited monocyte-derived alveolar macrophages and arginine depletion

F. Chen, D. W. El-Naccache, J. J. Ponessa, A. Lemenze, V. Espinosa, W. Wu, K. Lothstein, L. Jin, O. Antao, J. S. Weinstein, P. Damani-Yokota, K. Khanna, P. J. Murray, A. Rivera, M. C. Siracusa, W. C. Gause

This study identifies lung macrophages that kill helminths by depleting arginine through differential activation of recruited monocyte-derived alveolar macrophages.

bioRxiv · Oct 2, 2020 · PreprintImmunology