Author

Y. Kumamoto

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Immunology· 3 Biophysics· 2

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 5 Research Focus:cell type annotation· 4 Organism:mouse· 3 Research Focus:cell signaling & trafficking· 2 Research Focus:host-pathogen & immune response· 2 Assay:imaging· 2 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1

Frequent Co-Authors

H. Tanaka· 2 shared K. Fujita· 2 shared K. Mizushima· 2 shared K. Mochizuki· 2 shared M. Yamanaka· 2 shared N. I. Smith· 2 shared N. Tatsumi· 2 shared S. Tamura· 2 shared

Activity by Year

2020-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersBiophysics

H. Tanaka

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Raman microscopy of cryofixed biological specimens for high-resolution and high-sensitivity chemical imaging

K. Mizushima, Y. Kumamoto, S. Tamura, M. Yamanaka, K. Mochizuki, M. Li, S. Egoshi, K. Dodo, Y. Harada, N. I. Smith, M. Sodeoka, H. Tanaka, K. Fujita

This study improves Raman microscopy's signal-to-noise ratio and resolution by imaging cryofixed biological specimens, enabling high-content chemical imaging under physiological conditions.

bioRxiv · Nov 15, 2023 · PreprintBiophysics

Rapid activation of IL-2 receptor signaling by CD301b+DC-derived IL-2 dictates the outcome of helper T cell differentiation

N. Tatsumi, J. El-Fenej, A. Davila-Pagan, Y. Kumamoto

The paper identifies CD301b+ DC-derived IL-2 as a key driver of Th2 differentiation by activating IL-2 receptor signaling in CD4 T cells, while inhibiting T follicular helper fate.

bioRxiv · Oct 26, 2023 · PreprintImmunology

Time-deterministic cryo-optical microscopy

M. Yamanaka, K. Tsuji, Y. Kumamoto, S. Tamura, W. Miyamura, T. Kubo, K. Mizushima, K. Kono, H. Hirano, K. Sugiura, S.-i. Fukushima, T. Kunimoto, K. Nishida, K. Mochizuki, Y. Harada, , K. Fujita

The paper introduces a technique to rapidly freeze biological systems during optical observation, enabling detailed time-specific analysis of cellular dynamics at high spatial resolution.

bioRxiv · Aug 1, 2023 · PreprintBiophysics

A helminth mimic of TGF-β, TGM, enhances regenerative cutaneous wound healing and modulates immune cell recruitment and activation

K. E. Lothstein, F. Chen, P. Mishra, D. J. Smyth, W. Wu, A. Lemenze, Y. Kumamoto, R. M. Maizels, W. C. Gause

This study shows that TGM, a helminth-derived TGF-β mimic, accelerates wound healing and reprograms macrophage activation through TGF-β receptor interactions.

bioRxiv · Sep 24, 2022 · PreprintImmunology

Optimal CD4T Cell Priming in Lymph Nodes Requires Repertoire Scanning by CD301b+ Migratory cDC2 Cells

N. Tatsumi, A. L. Codrington, Y. Kumamoto

This study shows that CD301b+ migratory cDC2 cells retain polyclonal CD4T cells in lymph nodes, enabling efficient scanning and priming of antigen-specific clones.

bioRxiv · Aug 31, 2020 · PreprintImmunology