Structural basis for distinct inflammasome complex assembly by human NLRP1 and CARD8
Q. Gong, K. Robinson, C. Xu, J. Zhang, Z. Z. Boo, D. E. T. Teo, Y. Zhang, J. S. Y. Lim, W. I. Goh, G. Wright, F. L. Zhong, B. Wu, B. Reversade
This study reveals the structural mechanisms by which NLRP1 and CARD8 assemble distinct inflammasome complexes through unique CARD domain interactions.
bioRxiv · Jun 17, 2020Immunology