Author

D. E. T. Teo

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:development & morphogenesis· 1 Research Focus:host-pathogen & immune response· 1 Assay:structural biology· 1

Frequent Co-Authors

B. Reversade· 2 shared F. L. Zhong· 2 shared K. Robinson· 2 shared B. V. Au· 1 shared B. Wu· 1 shared C. K. Lim· 1 shared C. Xu· 1 shared D. Y. Wang· 1 shared

Activity by Year

2020-2020 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersImmunology

B. Reversade

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Author profile →

2 papers

Recent·Most cited

Direct cleavage of human NLRP1 by enteroviral 3C protease triggers inflammasome activation in airway epithelium

K. Robinson, D. E. T. Teo, K. S. Tan, G. A. Toh, H. H. Ong, C. K. Lim, K. Lay, B. V. Au, T. S. Lew, J. J. H. Chu, V. T. K. Chow, D. Y. Wang, F. L. Zhong, B. Reversade

The paper identifies enteroviral 3C proteases as the first cognate PAMP ligand for human NLRP1, showing they trigger inflammasome activation and airway inflammation.

bioRxiv · Oct 14, 2020 · PreprintImmunology

Structural basis for distinct inflammasome complex assembly by human NLRP1 and CARD8

Q. Gong, K. Robinson, C. Xu, J. Zhang, Z. Z. Boo, D. E. T. Teo, Y. Zhang, J. S. Y. Lim, W. I. Goh, G. Wright, F. L. Zhong, B. Wu, B. Reversade

This study reveals the structural mechanisms by which NLRP1 and CARD8 assemble distinct inflammasome complexes through unique CARD domain interactions.

bioRxiv · Jun 17, 2020Immunology