Author

W. J. McCarthy

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1

Signature Assays, Organisms & Methods

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Organism:bacteria (other)· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Research Focus:protein structure prediction· 1 Approach:wet-lab / biochemical assay· 1

Frequent Co-Authors

A. G. Coyne· 1 shared C. Abell· 1 shared C. Spry· 1 shared J. A. Boland· 1 shared J. C. Evans· 1 shared J. El Bakali· 1 shared M. Blaszczyk· 1 shared M. V. B. Dias· 1 shared

Activity by Year

2020-2020 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperBiochemistry

A. G. Coyne

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1 paper

Recent·Most cited

Chemical validation of Mycobacterium tuberculosis phosphopantetheine adenylyltransferase using fragment linking and CRISPR interference

J. El Bakali, M. Blaszczyk, J. C. Evans, J. A. Boland, W. J. McCarthy, M. V. B. Dias, A. G. Coyne, V. Mizrahi, T. L. Blundell, C. Abell, C. Spry

This study identifies inhibitors of MtbPPAT, a key enzyme in CoA biosynthesis, using fragment linking and CRISPR interference to validate it as a potential anti-TB drug target.

bioRxiv · Sep 4, 2020Biochemistry