W. Liu

This study differentiates urine-derived induced pluripotent stem cells from a diabetic patient into neuron, astrocyte, and microvascular endothelial cells to create an in vitro disease model for studying diabetes-related CNS complications.

This paper introduces a method for fast and accurate polarization and polarity imaging using polarized structured illumination, improving measurement accuracy and speed compared to conventional techniques.

The paper analyzes the miRNA-mRNA network regulated by LMP1 in NPC using microarray data to identify differentially expressed miRNAs and genes and construct interaction models.

This study shows that GIGANTEA recruits UBP12 and UBP13 to the ZTL complex to stabilize clock proteins during the day.

This study extends the in vivo haploid induction system from diploid maize to hexaploid wheat by knocking out homologous genes, achieving 2%-3% haploid induction with 30%-60% seed setting rate.

This study uses single-cell analysis to evaluate antiviral therapeutics, revealing efficacy and insights into drug resistance evolution and viral lifecycle impact.

This study shows that the I232T SNP in FcγRIIB causes structural changes that reduce ligand binding, contributing to SLE pathogenesis.

This study shows ionomycin treatment rescues osteoporosis in HPP by restoring Ca2+ influx via ALPL-mediated L-type Ca2+ channel trafficking in BMSCs.

The paper uses decoy E3 ubiquitin ligases to identify new regulators of the plant circadian clock, showing redundancy in PUB59 and PUB60's role in gene splicing and circadian period control.

This paper introduces high-resolution light-field microscopy for live-cell imaging with subcellular resolution and fast volumetric acquisition.

This study identifies NudCL2 as a cochaperone that stabilizes cohesin subunits by modulating Hsp90 ATPase activity, preventing mitotic defects and sister chromatid separation.

This study identifies GlnR as a nitrogen regulator that directly represses the prpDBC operon involved in methylcitrate cycle in M. smegmatis, linking nitrogen metabolism to carbon metabolism and affecting bacterial growth and macrophage survival.

The paper investigates the two-step binding kinetics of tRNAGly by the glyQS T-box riboswitch and identifies structural elements that regulate each step.

The paper investigates SAM-SAM domain interactions in Eph receptors and identifies SAMD5 as a new binding partner, explaining disease-related mutations.

The paper identifies type-2 CD8+ T cells (Tc2) enriched in severe eosinophilic asthma and shows PGD2 and LTE4 drive their recruitment and activation, contributing to eosinophilia.

BaalChIP corrects allele-specific ChIP-seq analysis for copy number variation in cancer genomes, improving detection of regulatory variants.