Author

S. Jia

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 3 Cell Biology· 3 Cancer Biology· 2 Immunology· 2 Plant Biology· 2 Biophysics· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 11 Research Focus:differential expression· 7 Research Focus:cell type annotation· 6 Organism:human· 6 Approach:statistical model· 4 Assay:bulk RNA-seq· 3 Assay:imaging· 3 Organism:mouse· 3

Frequent Co-Authors

Y. Li· 4 shared S. Li· 3 shared H. Wang· 2 shared J. Wang· 2 shared L. Liang· 2 shared Y. Meng· 2 shared Y. Wei· 2 shared A. Arunagiri· 1 shared

Activity by Year

2018-2023 · peak 4/yr

Co-Author Collaboration Network

10 top collaborators · 6 mutual co-author links

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4 shared papersBioengineering

Y. Li

Mutual co-authors in cluster

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15 papers

Recent·Most cited

PPARγ controls ESCRT-dependent fibroblast-like synoviocyte exosome biogenesis and Alleviates Chondrocyte Osteoarthritis Mediated by Exosomal ANXA1

S. Jia, Y. Yang, J. Liu, Y. Wei, Z. Wang, L. Yue, L. Bai

This study shows that PPARγ enhances exosome biogenesis in fibroblast-like synoviocytes via the ESCRT pathway, and these exosomes containing ANXA1 alleviate osteoarthritis by inhibiting ERK phosphorylation and chondrocyte apoptosis.

bioRxiv · Nov 19, 2023Cell Biology

Genetically Encodable in situ Gelation Redox-Responsive Collagen-Like Protein Hydrogel for Accelerating Diabetic Wound Healing

S. Jia, J. Wang, X. Wang, X. Liu, S. Li, Y. Li, J. Li, J. Wang, S. Man, Z. Guo, Y. Sun, Z. Jia, L. Wang, X. Li

This study develops a genetically encoded redox-responsive collagen-like protein hydrogel that accelerates diabetic wound healing by enhancing cell viability and reducing oxidant stress.

bioRxiv · May 29, 2023 · PreprintBioengineering

N6-methyladenosine demethylase FTO serves as an indicator for predicting prognosis and immunotherapy response in individuals with gastric cancer

S. Jia, H. Zhou, K. Li, Y. Li

This study identifies FTO as a prognostic marker and immunotherapy predictor in gastric cancer, showing its association with poor outcomes and immune evasion.

bioRxiv · May 15, 2023 · PreprintCancer Biology

Insm1 regulates the development of mTECs and immune tolerance

W. Tao, Y. Wei, Z. Ye, J. Wang, W. Yang, G. Yu, J. Xiong, S. Jia

This study shows that Insm1 regulates mTEC development and immune tolerance by interacting with Aire and affecting gene expression.

bioRxiv · Jan 14, 2023Immunology

Aberrant DNA repair is a vulnerability in histone H3.3-mutant brain tumors

B. Rondinelli, G. Giacomini, S. Piquet, O. Chevallier, J. Dabin, S.-K. Bai, B. Kim, R. Siddaway, B. Raught, E. Coyaud, C.-M. Shan, R. J. D. Reid, T. Toda, R. Rothstein, T. Wilhelm, , S. E. Polo

The paper identifies aberrant DNA repair as a vulnerability in H3.3-mutant brain tumors, showing that PNKP-mediated repair is specific to mutant cells and offers therapeutic potential.

bioRxiv · Sep 29, 2022 · PreprintCancer Biology

Evolution of m6A related genes in insects and function of METTL3 in embryonic development of silkworm.

S. Liu, S. Jia, Y. Li, K. Hu, Y. Lu, J. Tao, Y. Xu, H. Wang

This study investigates the evolutionary conservation of m6A-related genes in insects and identifies METTL3's role in silkworm embryonic development through functional analysis.

bioRxiv · Aug 29, 2022Evolutionary Biology

Restoration of PITPNA in Type 2 diabetic human islets reverses pancreatic beta-cell dysfunction

Y.-T. Yeh, C. Sona, X. Yan, A. Pathak, M. I. McDermott, Z. Xie, L. Liu, A. Arunagiri, Y. Wang, A. Cazenave-Gassiot, A. Ghosh, F. von Meyenn, S. Kumarasamy, S. M. Najjar, S. Jia, , M. N. Poy

The paper shows restoring PITPNA in T2D human islets reverses beta-cell dysfunction by improving insulin granule maturation and glucose-stimulated insulin secretion.

bioRxiv · Jul 6, 2022Cell Biology

Ticagrelor combined with aspirin displays the signature of regulating the gut microbiome in consistence with improving the immuno-inflammatory response in atherosclerosis

Z. Bai, Q. Zhang, Y. Liu, Y. Zhao, R. Yan, L. Yang, H. Ma, Y. Ren, T. Wang, Y. Li, Y. Liu, X. Jiang, R. Wang, S. Jia, X. Zhang, H. Wang

The paper was withdrawn due to insufficient cell culture data to clarify the mechanism of ticagrelor and aspirin's effect on the gut microbiome and immuno-inflammatory response in atherosclerosis.

bioRxiv · Jun 22, 2022 · PreprintImmunology

DNA Self-Assembled Plasmonic Nanodiamonds for Biological Sensing

L. Liang, P. Zheng, S. Jia, K. Ray, Y. Chen, I. Barman

This study develops plasmon-enhanced nanodiamonds (PEN) for biological imaging by using DNA self-assembly to improve brightness and temporal resolution of NV centers.

bioRxiv · Nov 9, 2021 · PreprintBiophysics

Repression of MAPK/Erk signaling by Efnb2-Ephb4-Rasa1 is required for lymphatic valve formation

S. Jia, Y. Meng, T. Lv, J. Zhang, A. Meng

This study identifies the role of Efnb2-Ephb4-Rasa1 in repressing MAPK/Erk signaling to regulate lymphatic valve formation and suggests potential therapeutic targets.

bioRxiv · Oct 17, 2021 · PreprintDevelopmental Biology

A missense KCNQ1 Mutation Impairs Insulin Secretion in Neonatal Diabetes

Z. Zhou, M. Gong, A. Pande, U. Lisewski, T. Röpke, B. Purfürst, L. Liang, S. Jia, S. Frühler, A. Margineanu, C. Zeng, H. Zhu, P. Kühnen, S. Khodaverdi, W. Krill, , Z. Izsvak

This study identifies a KCNQ1 mutation causing neonatal diabetes by impairing β-cell function and survival through electrophysiological and transcriptomic analyses.

bioRxiv · Aug 24, 2021 · PreprintCell Biology

A dataset of speed-resolved blood perfusion and oxygen saturation in human skin response to thermal stimulation

S. Jia, X. Song, W. Zhang, G. Wang

This paper presents a dataset of speed-resolved blood perfusion and oxygen saturation in human skin under thermal stimulation and control conditions.

bioRxiv · Mar 4, 2020 · PreprintBioengineering

Mapping of transgenic alleles in plants using a Nanopore-based sequencing strategy

S. Li, S. Jia, L. Hou, H. Nguyen, S. Sato, D. Holding, E. Cahoon, C. Zhang, T. Clemente, B. Yu

The paper introduces a Nanopore-based sequencing method to rapidly map transgenic alleles in the soybean genome, offering a high-throughput and cost-efficient approach.

bioRxiv · Jan 23, 2019Plant Biology

Fast, volumetric live-cell imaging using high-resolution light-field microscopy

H. Li, C. Guo, D. Kim-Holzapfel, W. Li, Y. Altshuller, B. Schroeder, W. Liu, Y. Meng, J. French, K.-I. Takamaru, M. Frohman, S. Jia

This paper introduces high-resolution light-field microscopy for live-cell imaging with subcellular resolution and fast volumetric acquisition.

bioRxiv · Oct 10, 2018Bioengineering

Analysis of Transcripts and splice isoforms in Red Clover (Trifolium pratense L.) by single-molecule long-read sequencing

Y. Chao, J. Yuan, S. Li, S. Jia, L. Han, L. Xu

This study uses single-molecule long-read sequencing to analyze red clover transcriptome, identifying novel splice isoforms, alternative splicing events, and non-coding RNAs.

bioRxiv · May 25, 2018Plant Biology