Author

W. R. Arnold

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2

Signature Assays, Organisms & Methods

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Organism:human· 2 Research Focus:chromatin & epigenetic regulation· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Assay:proteomics· 1 Approach:statistical model· 1

Frequent Co-Authors

A. Das· 1 shared A. Frost· 1 shared A. S. Mancino· 1 shared D. Julius· 1 shared E. Tajkhorshid· 1 shared F. R. Moss· 1 shared H. Hu· 1 shared J. L. Baylon· 1 shared

Activity by Year

2020-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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1 shared paperBiochemistry

A. Das

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2 papers

Recent·Most cited

Structural basis of TRPV1 modulation by endogenous bioactive lipids

W. R. Arnold, A. S. Mancino, F. R. Moss, A. Frost, D. Julius, Y. Cheng

This study identifies a lipid-binding pocket in TRPV1 and shows that its occupancy by phosphoinositides modulates channel activity, with lipid ejection triggering activation.

bioRxiv · May 11, 2023Biochemistry

Anti-inflammatory dopamine- and serotonin-based endocannabinoid epoxides reciprocally regulate cannabinoid receptors and the TRPV1 channel

W. R. Arnold, L. N. Carnevale, Z. Xie, J. L. Baylon, E. Tajkhorshid, H. Hu, A. Das

This paper identifies novel endocannabinoid epoxides that modulate TRPV1 and cannabinoid receptors, reducing inflammation and offering potential for new therapeutics.

bioRxiv · May 5, 2020Biochemistry