Author

W. R. MacLellan

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:mouse· 2 Research Focus:cell type annotation· 1 Assay:DNA methylation· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Assay:imaging· 1 Organism:plant (other)· 1

Frequent Co-Authors

C. E. Murry· 2 shared D. El-nachef· 2 shared X. Yang· 2 shared A. Bertero· 1 shared A. Futakuchi-Tsuchida· 1 shared A. Jayabalu· 1 shared A. M. Martinson· 1 shared B. C. Knollmann· 1 shared

Activity by Year

2019-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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2 shared papersPharmacology & Toxicology

C. E. Murry

Mutual co-authors in cluster

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3 papers

Recent·Most cited

Dynamic Visualization of DNA Methylation in Cell Cycle Genes during iPSC Cardiac Differentiation

N. Li, B. T. Nguyen, Z. Zhang, W. R. MacLellan, Y. Zhang

The paper uses a genomic DNA methylation reporter system to track dynamic DNA methylation changes in cell cycle genes during iPSC cardiac differentiation, showing hypermethylation correlates with gene expression reduction.

bioRxiv · Jan 17, 2024Cell Biology

Pharmacologic Therapy for Engraftment Arrhythmia Induced by Transplantation of Human Cardiomyocytes

K. Nakamura, L. E. Neidig, X. Yang, G. J. Weber, D. El-nachef, H. Tsuchida, S. Dupras, F. A. Kalucki, A. Jayabalu, A. Futakuchi-Tsuchida, D. S. Nakamura, S. Marchiano, A. Bertero, M. R. Robinson, K. Cain, , C. E. Murry

This study shows that amiodarone and ivabradine together prevent cardiac death and reduce arrhythmia burden in a porcine model of engraftment arrhythmia after human cardiomyocyte transplantation.

Stem Cell Reports · Oct 1, 2021Peer-reviewedPharmacology & Toxicology

High-Resolution 3D Fluorescent Imaging of Intact Tissues

D. El-Nachef, A. M. Martinson, X. Yang, C. E. Murry, W. R. MacLellan

This paper describes an optimized method for high-resolution 3D fluorescent imaging of human and rodent tissues, achieving sub-micron resolution and imaging depth over 100 micrometers.

bioRxiv · Nov 26, 2019 · PreprintCell Biology