Author

W. Reik

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2 Biophysics· 1

Signature Assays, Organisms & Methods

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Assay:DNA methylation· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Approach:deep learning· 1 Research Focus:differential expression· 1 Organism:Drosophila· 1

Frequent Co-Authors

S. Rulands· 2 shared A. Alsina· 1 shared A. Berenguer· 1 shared A. M. Hashtroud· 1 shared A.-K. Stark· 1 shared C. Gregorio-Rodriguez· 1 shared C. Stephan-Otto Attolini· 1 shared D. Chondronasiou· 1 shared

Activity by Year

2020-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 16 mutual co-author links

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2 shared papersCell Biology

S. Rulands

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Single cell DNA methylation ageing in mouse blood

M. J. Bonder, S. Clark, F. Krueger, S. Luo, J. Agostinho de Sousa, A. M. Hashtroud, T. M. Stubbs, A.-K. Stark, S. Rulands, O. Stegle, W. Reik, F. von Meyenn

This study develops a single-cell DNA methylation age predictor using a large multi-omics dataset from mouse blood, revealing epigenetic age heterogeneity and differences across blood cell types.

bioRxiv · Jan 30, 2023 · PreprintCell Biology

Multi-omic rejuvenation of naturally aged tissues by a single cycle of transient reprogramming

D. Chondronasiou, D. Gill, L. Mosteiro, R. G. Urdinguio, A. Berenguer, M. Aguilera, S. Durand, F. Aprahamian, N. Nirmalathasan, M. Abad, D. E. Martin-Herranz, C. Stephan-Otto Attolini, N. Prats, G. Kroemer, M. F. Fraga, , M. Serrano

This study shows that a single cycle of transient OSKM expression reverses aging-related DNA methylation, transcriptional, and metabolic changes in multiple tissues of aged mice.

bioRxiv · Jan 20, 2022Cell Biology

Specialisation and plasticity in a primitively social insect

S. Patalano, A. Alsina, C. Gregorio-Rodriguez, M. Bachman, S. Dreier, I. Hernando-Herraez, P. Nana, S. Balasubramanian, S. Sumner, W. Reik, S. Rulands

The paper shows how a primitive social insect achieves both specialization and plasticity by integrating antagonistic processes across different scales.

bioRxiv · Mar 31, 2020 · PreprintBiophysics