Author

M. F. Fraga

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Assay:DNA methylation· 2 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1 Research Focus:metabolism & bioenergetics· 1 Assay:metabolomics· 1

Frequent Co-Authors

A. Astudillo· 1 shared A. Berenguer· 1 shared A. Brana· 1 shared A. F. Fernandez· 1 shared A. Rodriguez· 1 shared B. Gallego· 1 shared C. Huergo· 1 shared C. Robledo· 1 shared

Activity by Year

2022-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperCancer Biology

A. Astudillo

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

A personalized medicine approach identifies enasidenib as an efficient treatment for IDH2 mutant chondrosarcoma

V. Rey, J. Tornin, J. J. Alba-Linares, C. Robledo, D. Murillo, A. Rodriguez, B. Gallego, C. Huergo, A. Brana, A. Astudillo, D. Heymann, A. F. Fernandez, M. F. Fraga, J. Alonso, R. Rodriguez

This study identifies enasidenib as an effective treatment for IDH2 mutant chondrosarcoma through personalized medicine approaches involving sequencing, cell line models, and in vitro/in vivo testing.

eBioMedicine · Apr 1, 2024Peer-reviewedCancer Biology

Multi-omic rejuvenation of naturally aged tissues by a single cycle of transient reprogramming

D. Chondronasiou, D. Gill, L. Mosteiro, R. G. Urdinguio, A. Berenguer, M. Aguilera, S. Durand, F. Aprahamian, N. Nirmalathasan, M. Abad, D. E. Martin-Herranz, C. Stephan-Otto Attolini, N. Prats, G. Kroemer, M. F. Fraga, , M. Serrano

This study shows that a single cycle of transient OSKM expression reverses aging-related DNA methylation, transcriptional, and metabolic changes in multiple tissues of aged mice.

bioRxiv · Jan 20, 2022Cell Biology