Author

W.-D. Heyer

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 4

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:yeast· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:chromatin & epigenetic regulation· 1 Assay:cryo-EM· 1 Research Focus:development & morphogenesis· 1 Assay:DNA methylation· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

F. Chedin· 2 shared S. R. Hartono· 2 shared S. Shah· 2 shared A. Gallardo-Godoy· 1 shared A. Piazza· 1 shared A. R. Renslo· 1 shared C. Bryant· 1 shared J. L. Davies· 1 shared

Activity by Year

2019-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 16 mutual co-author links

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2 shared papersBiochemistry

F. Chedin

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Author profile →

4 papers

Recent·Most cited

Local structural dynamics of Rad51 protomers revealed by cryo-electron microscopy of Rad51-ssDNA filaments

J. Liu, S. Gore, W.-D. Heyer

This paper uses cryo-EM to determine the structure of Rad51-ssDNA filaments in budding yeast, revealing local structural dynamics and conformational changes in Rad51 protomers.

bioRxiv · May 6, 2024Biochemistry

Rdh54/Tid1 Inhibits Rad51-Rad54-Mediated D-loop Formation and Limits D-loop Length

S. Shah, S. R. Hartono, A. Piazza, V. Som, W. Wright, F. Chedin, W.-D. Heyer

This study shows Rdh54 inhibits Rad51-Rad54-mediated D-loop formation and limits D-loop length in yeast, with implications for cell survival and mating-type switching.

bioRxiv · May 20, 2020Biochemistry

NON-DENATURING BISULFITE TREATMENT AND SINGLE-MOLECULE REAL-TIME SEQUENCING REVEALS D-LOOP FOOTPRINTS, THEIR LENGTH, POSITION AND DISTRIBUTION

S. Shah, S. R. Hartono, F. Chedin, W.-D. Heyer

bioRxiv · May 20, 2020Biochemistry

Small molecule inhibitors of a human recombination-associated ATPase, RAD54

K. T. Ehmsen, K. K. H. Ang, W. D. Wright, J. L. Davies, Y. Younis, Y. Birman, C. Bryant, A. Gallardo-Godoy, A. R. Renslo, R. J. Neitz, M. R. Arkin, W.-D. Heyer

This study identifies small molecule inhibitors of the human RAD54 ATPase, which is involved in homologous recombination, and evaluates their effects on DNA repair and cancer cell survival.

bioRxiv · Apr 19, 2019 · PreprintBiochemistry