LNS8801: An enantiomerically pure agonist of the G protein-coupled estrogen receptor suitable for clinical development
Christopher A. Natale, Sophia Mercado, Richard Zhuang, Cristina Aguirre‐Portolés, Israel Olayide, Christopher Kent Arnatt, John T. Seykora, Tina K. Garyantes, Wayne Luke, Todd W. Ridky
This paper identifies LNS8801, a pure enantiomer of G-1 that acts as a GPER agonist, showing cancer suppression in preclinical models and potential as a therapeutic with a predictive biomarker.
Cancer Research Communications · Mar 11, 2025Peer-reviewedCancer Biology