Christopher Kent Arnatt

The paper identifies alkamines as a previously hidden class of metabolites formed via reductive amination, revealing significant gaps in metabolomics and drug metabolism understanding.

This study identifies GPR183 as a driver of peripheral sensitization in rodents and humans, showing its role in pain pathways through immune cell activation and highlighting its potential as a therapeutic target.

This paper identifies LNS8801, a pure enantiomer of G-1 that acts as a GPER agonist, showing cancer suppression in preclinical models and potential as a therapeutic with a predictive biomarker.

This study predicts the structure of the human mitochondrial pyruvate carrier and investigates inhibitor binding to guide the development of more specific therapeutic agents.