NuMA promotes constitutive heterochromatin compaction by stabilizing linker histone H1 on chromatin
Yao Wang, Wenxue Zhao, Jiahao Niu, Cuifang Liu, Xiaotian Wang, Weihong Yuan, Shanshan Ai, Wolfgang P. Baumeister, Guohong Li, Aibin He, Peng Xu, Cheng Li, Yujie Sun
This study identifies NuMA's role in stabilizing linker histone H1 on chromatin to promote heterochromatin compaction and maintain epigenetic repression.
Cell Reports · Jan 23, 2026Peer-reviewedBiophysics