Author

Wendy J. Mack

University of Southern California;

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

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Evolutionary Biology· 1

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Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Organism:mouse· 1 Assay:proteomics· 1 Approach:statistical model· 1

Frequent Co-Authors

Amin HaghaniiD· 1 shared Amy ChristenseniD· 1 shared Annie Hiniker· 1 shared Boyang LiiD· 1 shared Caleb Finch· 1 shared Changhan LeeiD· 1 shared Christian J. PikeiD· 1 shared Claire S. ChungiD· 1 shared

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2026-2026 · peak 1/yr

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10 top collaborators · 45 mutual co-author links

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1 shared paperEvolutionary Biology

Amin HaghaniORCID

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1 paper

Recent·Most cited

ApoE isoforms establish distinct antioxidant trajectories across the aging brain

Sarah J Shemtov, Mafalda Cacciottolo, Amy Christensen, Boyang Li, Amin Haghani, Michelle C. Rice, Herbert Anson, Claire S. Chung, Whitaker Cohn, Hongqiao Zhang, Wendy J. Mack, Annie Hiniker, Changhan Lee, Todd E. Morgan, Elizabeth Head, , Max A. Thorwald

This study shows ApoE isoforms influence antioxidant pathways differently across aging, with ApoE4 showing stronger transcriptional responses but less effective protein production, linking to neurodegenerative risk.

bioRxiv · Nov 9, 2026 · PreprintEvolutionary Biology