Author

Wenwen Xin

Academy of Military Medical Sciences

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Molecular Biology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Assay:DNA methylation· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

Bing YuaniD· 1 shared Chongzhao YouiD· 1 shared H. Eric XuiD· 1 shared Hongguang ReniD· 1 shared Jianhao XuiD· 1 shared Jinglin Wang· 1 shared Mingda HuiD· 1 shared Shimeng GuoiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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1 shared paperMolecular Biology

Bing YuanORCID

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2 papers

Recent·Most cited

Base-mismatched crRNA in CRISPR Enabled Universal One-pot Rapid Nucleic Acid Detection

Jianhao Xu, Wang Xin, Bing Yuan, Mingda Hu, Wenwen Xin, Jinglin Wang, Hongguang Ren, Yuan Yuan

This paper introduces a one-pot CRISPR-Cas12a diagnostic strategy using base-mismatched crRNA, enabling rapid and specific detection of pathogens without PAM re-design or costly modifications.

bioRxiv · Oct 1, 2026 · PreprintMolecular Biology

Molecular Mechanism of pH Sensing and Activation in GPR4 Reveals Proton-Mediated GPCR Signaling

Chongzhao You, Shimeng Guo, Tianwei Zhang, Xinheng He, Tianyu Gao, Wenwen Xin, Zining Zhu, Yujie Lu, Youwei Xu, Zhen Li, Yumu Zhang, Xi Cheng, Yi Jiang, Xin Xie, H. Eric Xu

This study reveals the molecular mechanism of pH sensing and activation in GPR4 through cryo-EM structures, showing proton-driven conformational changes and lipid modulation.

Cell Discovery · Jun 24, 2025Peer-reviewedMolecular Biology