Author

Wenzhu Qi

Purdue University West Lafayette

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Neuroscience· 2 Biophysics· 1

Signature Assays, Organisms & Methods

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Assay:imaging· 3 Approach:experimental assay· 2 Research Focus:cell type annotation· 1 Approach:deep learning· 1 Organism:human· 1

Frequent Co-Authors

Abdelrahman M. SalemiD· 3 shared Jean-Christophe RochetiD· 3 shared Kevin John WebbiD· 3 shared Magaly Guzman Sosa· 2 shared Paula-Marie E. IveyiD· 2 shared Sehong MiniD· 2 shared Tamara L. Kinzer‐UrsemiD· 2 shared Alicia N. Scott· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

9 top collaborators · 36 mutual co-author links

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3 shared papersNeuroscience

Abdelrahman M. SalemORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

FLIM-FRET as a Molecular Filter for Membrane-Induced Aggregation

Abdelrahman M. Salem, Wenzhu Qi, Jean-Christophe Rochet, Kevin J. Webb

This paper introduces a FLIM-FRET method to quantify membrane-proximal alpha-synuclein aggregation in neurons by estimating per-cell lifetimes and mixture fractions using a hierarchical EM algorithm.

bioRxiv · Mar 15, 2026 · PreprintBiophysics

Mechanisms of Alpha-Synuclein Seeded Aggregation in Neurons Revealed by Fluorescence Lifetime Imaging

Paula-Marie E. Ivey, Magaly Guzman Sosa, Abdelrahman M. Salem, Sehong Min, Wenzhu Qi, Alicia N. Scott, Karin F.K. Ejendal, Tamara L. Kinzer‐Ursem, Jean‐Christophe Rochet, Kevin John Webb

This study uses fluorescence lifetime imaging to track alpha-synuclein aggregation in neurons, revealing that seeds disassemble before escaping endolysosomes and triggering cytosolic aggregation.

ACS Chemical Neuroscience · May 27, 2025Peer-reviewedNeuroscience

A FRET-Based FLIM Method to Probe Membrane-Induced Alpha-Synuclein Aggregation in Neurons

Paula-Marie E. Ivey, Abdelrahman M. Salem, Sehong Min, Wenzhu Qi, Magaly Guzman Sosa, Tamara L. Kinzer‐Ursem, Jean‐Christophe Rochet, Kevin John Webb

The paper develops a FLIM method to study membrane-induced alpha-synuclein aggregation in neurons, providing insights into Parkinson's disease mechanisms.

bioRxiv · Dec 19, 2024 · PreprintNeuroscience