Sehong Min

This study identifies treatment-associated biomarkers in pancreatic ductal adenocarcinoma using serum extracellular vesicle proteomics, finding platelet-related changes linked to survival and therapy response.

This paper develops a dual ion funnel interface to enhance sensitivity in single-cell proteomics, enabling reliable quantification of low-abundance proteins from single-cell samples.

This study uses fluorescence lifetime imaging to track alpha-synuclein aggregation in neurons, revealing that seeds disassemble before escaping endolysosomes and triggering cytosolic aggregation.

The paper develops a FLIM method to study membrane-induced alpha-synuclein aggregation in neurons, providing insights into Parkinson's disease mechanisms.

The paper investigates how phosphorylation near the pT181 epitope affects the affinity of pT181-tau antibodies, finding that phosphorylation at S184 or S185 can completely eliminate antibody binding.